mProX™ Human CAMKK2 Stable Cell Line
[CAT#: S01YF-1123-KX175]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
CAMKK2
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
CNS Research
Related Diseases
Parkinson Disease, Late-Onset. Among its related pathways are Calmodulin induced events and GPCR downstream signalling
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The enzyme calcium/calmodulin-dependent protein kinase kinase 2 is encoded by the CAMKK2 gene in humans. The gene's product is a member of the Ca++/calmodulin-dependent protein kinase subfamily and the serine/threonine-specific protein kinase family. By phosphorylating the downstream kinases CaMK1 and CaMK4, this protein contributes to the calcium/calmodulin-dependent (CaM) kinase cascade by enhancing their catalytic activity. CaMKK2 is an AMPK kinase in the hypothalamus that controls the synthesis of the hormone neuropeptide Y, which stimulates appetite. Through the downregulation of mu opioid receptors and the decrease of downstream signaling pathways, it also plays a significant role in the development of hyperalgesia and tolerance to opioid analgesic medications. The customized CAMKK2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Thomas
The CAMKK2 overexpression cell line design is well-optimized, and the provided documentation is comprehensive. It has saved me time and effort compared to traditional methods.
Mar 09 2023
Verified Customer
Karen
Most importantly, I would recommend this product to anyone who wants to research CAMKK2.
Oct 16 2022
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
