CAMK2A
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
Full Name | calcium/calmodulin dependent protein kinase II alpha |
Gene ID | Human: 815 Mouse: 12322 Rat: 25400 Monkey: 710540 |
UniProt ID | Human: Q9UQM7 Mouse: P11798 Rat: P11275 |
Alternative Names | CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha;calcium/calmodulin-dependent protein kinase type II subunit alpha;CaM kinase II alpha subunit;CaM-kinase II alpha chain;CaMK-II alpha subunit;caM kinase II subunit alpha;caMK-II subunit alpha;calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha;calcium/calmodulin-dependent protein kinase II alpha-B subunit;calcium/calmodulin-dependent protein kinase type II alpha chain |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CAMK2A Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: A549; CHO-K1; HEK293