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  • mProX™ Human CAMK2A Stable Cell Line

    [CAT#: S01YF-1123-KX170]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX1050 Magic™ Human CaMK2α(CAMK2A) in Vitro Assay Human Kinase Assay

    Product Information

    Target Protein
    CAMK2A
    Target Family
    Kinases/Enzyme Drug Discovery Assays and Products
    Target Protein Species
    Human
    Host Cell Type
    A549; CHO-K1; HEK293
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Reproductive Research
    Related Diseases
    Intellectual Developmental Disorder, Autosomal Recessive 63 and Intellectual Developmental Disorder, Autosomal Dominant 53. Among its related pathways are Calmodulin induced events and Signaling downstream of RAS mutants
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The enzyme that the CAMK2A gene produces is a member of the Ca2+/calmodulin-dependent protein kinase II subfamily and the serine/threonine-specific protein kinase family. At glutamatergic synapses, Ca2+ signaling is essential for multiple aspects of synaptic plasticity. The four chains that make up this enzyme are delta, gamma, beta, and alpha. Both spatial learning and hippocampus long-term potentiation (LTP) depend on the alpha chain expressed by this gene. This protein can be autophosphorylated to produce CaM-independent activity in addition to its calcium-calmodulin (CaM)-dependent activity. For this gene, two transcript variants encoding different isoforms have been found. The customized CAMK2A stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Carol

    The CAMK2A cell line was delivered promptly, and it performed exceptionally well in my assays. Jan 03 2020

    chat Verified Customer

    chat David

    The mouse CAMK2A KO cell line is easy to handle and has shown consistent performance in various experimental setups. Dec 13 2020

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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