CALCR
The CALCR receptor, which is a member of a subfamily of seven transmembrane-spanning G protein-coupled receptors, has a high affinity for the peptide hormone calcitonin. The encoded protein controls osteoclast-mediated bone resorption and helps to maintain calcium homeostasis. The onset of osteoporosis and differences in bone mineral density have been linked to polymorphisms in this gene. ADORA2B-mediated anti-inflammatory cytokine production and the transcriptional role of VDR in the regulation of osteoporosis-associated genes are two of its linked pathways. G protein-coupled receptor activity and transmembrane signaling receptor activity are GO annotations for this gene.
Full Name | Calcitonin receptor |
Gene ID | Human: 799 Mouse: 12311 Rat: 116506 Monkey: 701093 |
UniProt ID | Human: P30988 Mouse: Q60755 Rat: P32214 Monkey: A0A2K6UST5 |
Alternative Names | CRT; CTR; CT-R; CTR1; CALCR; Calcitonin receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR & RAMP1 Target Family: Calcitonin Receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR Target Family: Calcitonin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR Target Family: Calcitonin receptor Target Protein Species: Human Host Cell Type: HEK293F Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL Target Family: Calcitonin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL Target Family: Calcitonin Family Target Protein Species: Human Host Cell Type: MOLM-14;OCI-AML2;OCI-AML3;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL Target Family: Calcitonin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL; RAMP1 Target Family: Calcitonin receptor Target Protein Species: Human Host Cell Type: HEK293F Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL; RAMP3 Target Family: Calcitonin receptor Target Protein Species: Human Host Cell Type: HEK293F Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR; RAMP1 Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR; RAMP2 Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL; RAMP2 Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL; RAMP3 Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCRL Target Family: Calcitonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: RAMP1; CALCR Target Family: Calcitonin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: RAMP2; CALCR Target Family: Calcitonin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: RAMP3; CALCR Target Family: Calcitonin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CALCR Target Family: Calcitonin Family Target Protein Species: Human Host Cell Type: LN229;CHO-K1;HEK293