C5AR2
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.
Full Name | Complement C5a receptor 2 |
Gene ID | Human: 27202 Mouse: 319430 Rat: 445269 Monkey: 717209 |
UniProt ID | Human: Q9P296 Mouse: Q8BW93 Rat: Q695P6 Monkey: F7H5Z8 |
Alternative Names | C5L2; GPF77; GPR77; C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; C5AR2; Complement C5a receptor 2 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR2 Target Family: Anaphylatoxin Family Target Protein Species: Human Host Cell Type: LAD2;CHO-K1;HEK293