C5AR1
Enables G protein-coupled receptor activity and C5a receptor activity for the complement. involved in a number of functions, including the positive regulation of the ERK1 and ERK2 cascade, the complement component C5a signaling pathway, and mRNA transcription by RNA polymerase II. situated in the plasma membrane at the cell's basolateral side. Biomarker for severe acute respiratory syndrome, asthma, chronic obstructive lung disease, rhinitis, and Alzheimer's disease. Hypersensitivity Reaction Type Iii Disease and Mast-Cell Sarcoma are two conditions connected to C5AR1. The complement cascade and GPCR downstream signaling are two of its associated mechanisms. This gene has GO annotations for G protein-coupled receptor function and C5a binding in the complement system.
| Full Name | Complement C5a receptor 1 |
| Gene ID | Human: 728 Mouse: 12273 Rat: 113959 Monkey: 718056 |
| UniProt ID | Human: P21730 Mouse: P30993 Rat: P97520 Monkey: P79188 |
| Alternative Names | C5A; C5AR; C5R1; CD88; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a-R; complement component 5a receptor 1; C5AR1; Complement C5a receptor 1 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR1 Target Family: Anaphylatoxin Family Target Protein Species: Human Host Cell Type: A549M1;CHO-K1;HEK293
