BTK
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Full Name | Bruton tyrosine kinase |
| Gene ID | Human: 695 Mouse: 12229 Rat: 367901 Monkey: 703000 |
| UniProt ID | Human: Q06187 Mouse: P35991 Rat: Q5S255 |
| Alternative Names | AT; ATK; BPK; XLA; IMD1; AGMX1; IGHD3; PSCTK1;tyrosine-protein kinase BTK;B-cell progenitor kinase;Bruton agammaglobulinemia tyrosine kinase;Bruton's tyrosine kinase;agammaglobulinaemia tyrosine kinase;dominant-negative kinase-deficient Brutons tyrosine kinase |
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mProX™ Human BTK Stable Cell Line
[CAT#: S01YF-1123-KX165]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: BTK Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: AML; CHO-K1; HEK293
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