BMX
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene.
| Full Name | BMX non-receptor tyrosine kinase |
| Gene ID | Human: 660 Mouse: 12169 Rat: 367786 Monkey: 712722 |
| UniProt ID | Human: P51813 Mouse: P97504 Rat: |
| Alternative Names | ETK; PSCTK2; PSCTK3;cytoplasmic tyrosine-protein kinase BMX;BTK-like on X chromosome;Etk/Bmx cytosolic tyrosine kinase;NTK38 tyrosine kinase;bone marrow tyrosine kinase gene in chromosome X protein;epithelial and endothelial tyrosine kinase |
Product List
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mProX™ Human BMX Stable Cell Line
[CAT#: S01YF-1123-KX160]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: BMX Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: H1048; CHO-K1; HEK293
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