B2M
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Full Name | beta-2-microglobulin |
Gene ID | Human: 567 Mouse: 12010 Rat: 24223 Monkey: 712428 |
UniProt ID | Human: P61769 Mouse: P01887 Rat: P07151 Monkey: Q6V7J5 |
Alternative Names | IMD43; beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: B2M & FCGRT (L319A, L320A) Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: B2M & FCGRT Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: B2M Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: B2M Host Cell Type: Jurkat Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: B2M Host Cell Type: K562 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MC-38