AXL
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.
| Full Name | AXL receptor tyrosine kinase |
| Gene ID | Human: 558 Mouse: 26362 Rat: 308444 Monkey: 706123 |
| UniProt ID | Human: P30530 Mouse: Q00993 Rat: Q8VI99 |
| Alternative Names | ARK; UFO; JTK11; Tyro7;tyrosine-protein kinase receptor UFO;AXL oncogene;AXL transforming sequence/gene |
Product List
Loading...
mProX™ Human AXL Stable Cell Line
[CAT#: S01YF-1123-KX154]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AXL Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
Can't find the products you're looking for? Optimize our parameters for better results.
Filter By Tag
Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
