mProX™ Human AXL Stable Cell Line
[CAT#: S01YF-1123-KX154]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
AXL
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Immunology Research; Digestive and Renal Research; Reproductive Research
Related Diseases
Hypogonadotropic Hypogonadism 7 With Or Without Anosmia and Nk-Cell Enteropathy. Among its related pathways are GPCR Pathway and p70S6K Signaling
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The AXL gene in humans is responsible for encoding the enzyme tyrosine-protein kinase receptor. The original designation of the gene, UFO, was a reference to the unknown purpose of this protein. But since its discovery, studies on the mechanism and expression profile of AXL have made it a more desirable target, particularly for cancer treatments. Recent research has shown that AXL plays a critical role in immune escape and treatment resistance in cancer cells, which can result in aggressive and metastatic malignancies. AXL is a member of the TAM family of kinases, which also includes TYRO3 and MERTK. It is a cell surface receptor tyrosine kinase. The customized AXL stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Colbert
We have found this AXL cell line to be highly reliable and robust, producing consistent results.
Oct 15 2022
Verified Customer
Tobey
High quality and reliable AXL cell line.
Dec 09 2022
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
