AVPR2
The V2 receptor, which is part of the seven-transmembrane-domain G protein-coupled receptor superfamily and links to Gs to activate adenylate cyclase, is encoded by this gene. It is also known as the vasopressin receptor type 2 (V2 receptor). The V2 receptor is mostly found in the distal convoluted tubule and collecting ducts of the kidney, where it is expressed. In response to the pituitary hormone arginine vasopressin, it stimulates mechanisms that concentrate urine and keep the body's water balance in check. Nephrogenic Diabetes Insipidus develops when this gene's function is lost. The V2 receptor is expressed outside of the kidney as well, though its exact location in the tissue is unknown.
| Full Name | Arginine vasopressin receptor 2 |
| Gene ID | Human: 554 Mouse: 12000 Rat: 25108 Monkey: 697763 |
| UniProt ID | Human: P30518 Mouse: O88721 Rat: Q00788 Monkey: A0A5F7ZFB1 |
| Alternative Names | DI1; DIR; NDI; V2R; ADHR; DIR3; AVPR V2; antidiuretic hormone receptor; renal-type arginine vasopressin receptor; AVPR2; Arginine vasopressin receptor 2 |
Product List
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Magic™ Dog FLAG tagged AVPR2 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-1022-KX631]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin/Oxytocin Target Protein Species: Dog Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human AVPR2 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX241]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin and oxytocin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human AVPR2 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX242]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin and oxytocin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human AVPR2 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX113]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin and oxytocin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human AVPR2 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX56]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin and Oxytocin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human FLAG tagged AVPR2 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX629]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin/Oxytocin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Rabbit FLAG tagged AVPR2 HEK293T Cell Line, cAMP assay
[CAT#: S01YF-1022-KX630]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin/Oxytocin Target Protein Species: Rabbit Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
mProX™ Human AVPR2 Stable Cell Line
[CAT#: S01YF-0923-KX57]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AVPR2 Target Family: Vasopressin and Oxytocin Family Target Protein Species: Human Host Cell Type: MDCK; CHO-K1; HEK293
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