ASIC3
A member of the degenerin/epithelial sodium channel superfamily is encoded by this gene. Amiloride-sensitive sodium channels belonging to this family have extracellular N and C termini, two hydrophobic transmembrane sections, and a large extracellular loop with several cysteine residues that are spaced evenly apart. This gene's member, an acid sensor, may be crucial in the identification of long-lasting pH alterations. Additionally, this member and acid-sensing ion channel 2 have been seen to form a heteromeric relationship, both of which are proton-gated channels that are gadolinium-sensitive.
| Full Name | Acid sensing ion channel subunit 3 |
| Gene ID | Human: 9311 Mouse: 171209 Rat: 286920 Monkey: 714396 |
| UniProt ID | Human: Q9UHC3 Mouse: Q6X1Y6 Rat: O35240 Monkey: F6W6L6 |
| Alternative Names | ACCN3; TNaC1; DRASIC; SLNAC1; acid-sensing ion channel 3; acid sensing (proton gated) ion channel 3; amiloride-sensitive cation channel 3, testis; modulatory subunit of ASIC2a; neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; testis sodium channel 1; ASIC3; Acid sensing ion channel subunit 3 |
Product List
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Magic™ Human ASIC3 HEK293 Cell Line, Electrophysiology assay
[CAT#: S01YF-0822-KX128]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ASIC3 Target Family: Acid-Sensing-Neuronal Cation, Ligand-Gated Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Electrophysiology assay
Magic™ mPro Human ASIC3 Cell Line
[CAT#: S01YF-1122-KX68]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ASIC3 Target Family: Acid-Sensing-Neuronal Cation, Ligand-Gated Target Protein Species: Human
mProX™ Human ASIC3 Stable Cell Line
[CAT#: S01YF-1123-KX82]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ASIC3 Target Family: Acid-sensing Ion Channel Target Protein Species: Human Host Cell Type: PANC-1; BxPC-3; SW1990; AsPC-1; CHO-K1; HEK293
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