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ASIC3

A member of the degenerin/epithelial sodium channel superfamily is encoded by this gene. Amiloride-sensitive sodium channels belonging to this family have extracellular N and C termini, two hydrophobic transmembrane sections, and a large extracellular loop with several cysteine residues that are spaced evenly apart. This gene's member, an acid sensor, may be crucial in the identification of long-lasting pH alterations. Additionally, this member and acid-sensing ion channel 2 have been seen to form a heteromeric relationship, both of which are proton-gated channels that are gadolinium-sensitive.

Full Name Acid sensing ion channel subunit 3
Gene ID Human: 9311
Mouse: 171209
Rat: 286920
Monkey: 714396
UniProt ID Human: Q9UHC3
Mouse: Q6X1Y6
Rat: O35240
Monkey: F6W6L6
Alternative Names ACCN3; TNaC1; DRASIC; SLNAC1; acid-sensing ion channel 3; acid sensing (proton gated) ion channel 3; amiloride-sensitive cation channel 3, testis; modulatory subunit of ASIC2a; neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; testis sodium channel 1; ASIC3; Acid sensing ion channel subunit 3

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: ASIC3 Target Family: Acid-Sensing-Neuronal Cation, Ligand-Gated Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: ASIC3 Target Family: Acid-sensing Ion Channel Target Protein Species: Human Host Cell Type: PANC-1; BxPC-3; SW1990; AsPC-1; CHO-K1; HEK293
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