AR
The N-terminal domain, DNA-binding domain, and androgen-binding domain are the three primary functional domains of the androgen receptor protein, which is encoded by the more than 90 kb long androgen receptor gene. The protein acts as a transcription factor that is triggered by steroids and hormones. The receptor separates from supporting proteins after binding the hormone ligand, moves into the nucleus, dimerizes, and then activates transcription of androgen-responsive genes. The N-terminal transactivation domain of this gene's protein is encoded by two polymorphic trinucleotide repeat segments that code for polyglutamine and polyglycine tracts.
Full Name | Androgen receptor |
Gene ID | Human: 367 Mouse: 11835 Rat: 24208 Monkey: 574293 |
UniProt ID | Human: P10275 Mouse: P19091 Rat: P15207 Monkey: Q6QT55 |
Alternative Names | KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; androgen receptor; dihydrotestosterone receptor; nuclear receptor subfamily 3 group C member 4 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR1; ARRB2 Target Family: Free Fatty Acid Target Protein Species: Cynomolgus monkey Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: β-Arrestin Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR1 Target Family: Free Fatty Acid Target Protein Species: Cynomolgus monkey Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR2 Target Family: Free Fatty Acid Target Protein Species: Cynomolgus monkey Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR1 Target Family: Free Fatty Acid Target Protein Species: Dog Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR2 Target Family: Free Fatty Acid Target Protein Species: Dog Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: AR Target Family: Nuclear Receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ARV7 Target Family: Nuclear Receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C3AR1 Target Family: Complement peptide receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C3AR1 Target Family: Complement peptide receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR1 (W231L) Target Family: Anaphylatoxin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR1 Target Family: Anaphylatoxin Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR1 Target Family: Complement peptide receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5aR1 Target Family: Complement peptide receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR1 Target Family: Complement peptide receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR1 Target Family: Complement peptide receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: C5AR1 Target Family: Anaphylatoxin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKAR Target Family: Cholecystokinin receptor Target Protein Species: Human Host Cell Type: 1321N1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKAR Target Family: Cholecystokinin receptor Target Protein Species: Human Host Cell Type: 1321N1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKAR Target Family: Cholecystokinin Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKAR Target Family: Cholecystokinin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKAR Target Family: Cholecystokinin receptor Target Protein Species: Human Host Cell Type: HEK293T Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCKAR Target Family: Cholecystokinin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ETV6 & ARG Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR1 Target Family: Free Fatty Acid Receptors Target Protein Species: Human Host Cell Type: 1321N1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR1 Target Family: Free Fatty Acid Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR1 Target Family: Free fatty acid receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR1 Target Family: Free Fatty Acid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR2 Target Family: Free fatty acid receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR2 Target Family: Free Fatty Acid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FFAR3 Target Family: Free Fatty Acid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay