APLNR
The G protein-coupled receptor gene family includes APLNR. The encoded protein is linked to the angiotensin receptor but is actually an apelin receptor that blocks adenylate cyclase activity and functions as a counter-regulatory mechanism to angiotensin II's pressure-raising impact by having a hypertensive effect. It performs duties in the heart and central nervous system, glucose metabolism, embryonic development, tumor angiogenesis, and as an HIV-1 coreceptor. Its associated pathways include Class A/1 and GPCR downstream signaling (Rhodopsin-like receptors). This gene has annotations for G protein-coupled receptor activity and signaling receptor activity in the Gene Ontology (GO) database.
| Full Name | Apelin receptor |
| Gene ID | Human: 187 Mouse: 23796 Rat: 83518 Monkey: 706823 |
| UniProt ID | Human: P35414 Mouse: Q9WV08 Rat: Q9JHG3 Monkey: O97666 |
| Alternative Names | APJ; APJR; HG11; AGTRL1; APJ (apelin) receptor; APJ receptor; G protein-coupled receptor APJ; G-protein coupled receptor HG11; HG11 orphan receptor; angiotensin II receptor-like 1; angiotensin receptor-like 1; APLNR; Apelin receptor |
Product List
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Magic™ Human APLNR CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX364]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human APLNR CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX365]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human APLNR CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX24]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human APLNR U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX21]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Magic™ Human APLNR U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX106]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human FLAG tagged APLNR CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX206]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human FLAG tagged APLNR HEK293T Cell Line, cAMP assay
[CAT#: S01YF-1022-KX205]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
mProX™ Human APLNR Stable Cell Line
[CAT#: S01YF-0923-PY19]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: APLNR Target Family: Apelin Family Target Protein Species: Human Host Cell Type: 5-8F;HNE-1;CHO-K1;HEK293
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