ADRB1
The guanine nucleotide binding regulatory protein-coupled receptors known as ADRB1 receptors are a model family that mediates the physiological effects of the neurotransmitter norepinephrine and the hormone epinephrine. The heart is where beta-1 adrenoceptors are primarily found. This gene's specific polymorphisms have been proven to influence resting heart rate and may contribute to heart failure. Resting Heart Rate, Variation in and Short Sleep, and Familial Natural are diseases linked to ADRB1. ADORA2B-mediated anti-inflammatory cytokine production and Development Ligand-independent activation of ESR1 and ESR2 are among its associated mechanisms. This gene has PDZ domain binding and G protein-coupled receptor function as Gene Ontology (GO) annotations.
| Full Name | Adrenoceptor beta 1 |
| Gene ID | Human: 153 Mouse: 11554 Rat: 24925 Monkey: 100426598 |
| UniProt ID | Human: P08588 Mouse: P34971 Rat: P18090 Monkey: P47899 |
| Alternative Names | adrenergic, beta-1-, receptor; beta-1 adrenoceptor; beta-1 adrenoreceptorRHR; B1AR; FNSS2; ADRB1R; BETA1AR; ADRB1; Adrenoceptor beta 1 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB1 Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB1 Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB1 Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB1 Target Family: Adrenoceptors Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Tools
- Target Protein: ADRB1 Target Family: Adrenergic Family
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB1 Target Family: Adrenergic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB1 Target Family: Adrenergic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRB1 Target Family: Adrenergic Family Target Protein Species: Human Host Cell Type: Adipocyte;(TERT-hBA);CHO-K1;HEK293
