ACVRL1
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
| Full Name | activin A receptor like type 1 |
| Gene ID | Human: 94 Mouse: 11482 Rat: 25237 Monkey: 696471 |
| UniProt ID | Human: P37023 Mouse: Q61288 Rat: P80203 |
| Alternative Names | HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1;serine/threonine-protein kinase receptor R3;TGF-B superfamily receptor type I;activin A receptor type II-like 1;activin A receptor type IL;activin A receptor, type II-like kinase 1 |
Product List
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mProX™ Human ACVRL1 Stable Cell Line
[CAT#: S01YF-1123-KX144]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ACVRL1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: iPSCs; CHO-K1; HEK293
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