ACVR1B
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
| Full Name | activin A receptor type 1B |
| Gene ID | Human: 91 Mouse: 11479 Rat: 29381 Monkey: 696587 |
| UniProt ID | Human: P36896 Mouse: Q61271 Rat: P80202 |
| Alternative Names | ALK4; SKR2; ACTRIB; ACVRLK4;activin receptor type-1B;activin A receptor, type IB;activin A receptor, type II-like kinase 4;activin receptor-like kinase 4;serine/threonine-protein kinase receptor R2 |
Product List
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Magic™ Human ACVR1B(ALK4) Assay
[CAT#: S01YF-1122-KX1021]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: ACVR1B(ALK4) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human ACVR1B Stable Cell Line
[CAT#: S01YF-1123-KX143]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ACVR1B Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: PC; CHO-K1; HEK293
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