mProX™ Human ACVR1B Stable Cell Line

[CAT#: S01YF-1123-KX143]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Bulk Quote

Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1021	Magic™ Human ACVR1B(ALK4) in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

ACVR1B

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

PC; CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cancer Research; Cardiovascular Research

Related Diseases

Transposition Of The Great Arteries, Dextro-Looped and Pancreatic Cancer. Among its related pathways are Human Embryonic Stem Cell Pluripotency and Signal Transduction

Gene ID

UniProt ID

P36896

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The human ACVR1B gene encodes the protein known as activin receptor type-1B. Signals containing activin or activin-like ligands are transduced by ACVR1B or ALK-4. After binding to ACVR2A or ACVR2B, activin joins ACVR1B in a complex. Activins are structurally related signaling proteins that are dimeric growth and differentiation factors that are a member of the transforming growth factor-beta (TGF-beta) superfamily. A heteromeric complex of receptor serine kinases, comprising a minimum of two type I (I and IB) and two type II (II and IIB) receptors, is how activins transmit their signals. Type II receptors are necessary for ligand binding and type I receptor expression, while type I receptors are crucial for signaling. The customized ACVR1B stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat George

The ACVR1B cell line is easy to use, and the results obtained have been consistent and reliable. I would definitely recommend it to others. Mar 16 2023

chat Verified Customer

chat Carol

The ACVR1B cell line was easy to use, and the support team was responsive to our inquiries. May 02 2023

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

Related Products by Target

Online Inquiry

Thank you for your interest in mProX™ Human ACVR1B Stable Cell Line. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):

Estimated delivery time for your area;
Product sample or exclusive offer;
In-lab demonstration;

Creative Biolabs does not share your email address with third parties. Creative Biolabs will use your email address to confirm your identity and send you transaction-related emails, promotional and customer service emails in accordance with our privacy policy. You can change your email preferences at any time.