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  • mProX™ Human TRPV1 Stable Cell Line

    [CAT#: S01YF-1123-KX49]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    TRPV1
    Target Family
    TRPV
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    Digestive and Renal Research; Inflammation Research; Metabolic Research
    Related Diseases
    Pulpitis; Bladder Disease
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The TRPV1 gene in humans encodes a protein known as the transient receptor potential cation channel subfamily V member 1 (TRPV1), which is sometimes referred to as the capsaicin receptor and the vanilloid receptor 1. A component or mechanism of the mammalian somatosensory system is TRPV1. Numerous exogenous and endogenous physical and chemical stimuli can open this nonselective cation channel. TRPV1 activation results in a searing, excruciating feeling. Low pH, the endocannabinoid anandamide, N-oleyl-dopamine, and N-arachidonoyl-dopamine are some of its endogenous activators. TRPV1 receptors have been identified in numerous additional tissues, including the central nervous system, however they are mostly present in the nociceptive neurons of the peripheral nervous system. TRPV1 plays a role in both the integration of various painful stimuli and the transmission and regulation of pain. The customized TRPV1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Kevin

    I have confirmed in our lab that the cells have work. Jan 27 2023

    chat Verified Customer

    chat James

    We are very happy with the product and the turn around time, and would therefore order another reagent. May 23 2020

    chat Verified Customer

    FAQ

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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