mProX™ Human TRPM7 Stable Cell Line

[CAT#: S01YF-1123-KX62]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Ion Channel Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

TRPM7

Target Family

TRPM

Target Protein Species

Human

Host Cell Type

HNSCC; CHO-K1; HEK293

Target Classification

Ion Channel Cell Lines

Target Research Area

CNS Research; Cardiovascular Research

Related Diseases

Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex; Hypomagnesemia

Gene ID

54822

UniProt ID

Q96QT4

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

TRPM7 belongs to the transient receptor potential, or TRP, ion channel subfamily that is connected to melastatin. TRP channels are typically Ca2+-permeable, frequently controlled by G-protein-coupled receptors, and associated with numerous physiological functions, such as the recognition of chemical and physical inputs. There are three subtypes of TRP channels that have been identified: the short, long, and Osm-9 subtypes. TRPM7 and its associated TRPM6 belong to the long TRP subgroup. The protein kinase domain that is linked to the ion channel's C-terminus distinguishes TRPM6 and TRPM7 from other similar proteins. Recent research has shown that TRPM6 and TRPM7 are crucial for the uptake of Mg2+ and the maintenance of homeostasis in mammals. Additionally, TRPM7 seems to be involved in a wide range of different cellular processes. The customized TRPM7 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Kathleen

The TRPM7 Stable Cell Line is great for research. Apr 25 2023

chat Verified Customer

chat Dorothy

Flow cytometry is used to verify the surface expression of the TRPM7 protein, and qPCR is used to verify the engineering results at the mRNA level. Sep 22 2022

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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