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    mProX™ Human TLR3 Stable Cell Line

    [CAT#: S01YF-1023-PY209]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Immune Checkpoint Cell Lines

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    Host Cell Type:
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    Product Information

    Target Family
    Immune Checkpoint
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1
    Target Classification
    Immune Checkpoint Cell Lines
    Target Research Area
    Infectious Research
    Related Diseases
    Immunodeficiency 83 Viral Infections; Human Immunodeficiency Virus Type 1
    Gene ID
    Human:7098
    UniProt ID
    Human:O15455

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Toll-like receptor 3 (TLR3) is unique among TLRs due to its ability to recognize double-stranded RNA, a molecular signature of viral infections. This recognition is crucial for mounting antiviral responses. Recent studies have shown that TLR3 plays a vital role in defending against viral pathogens, including the herpes simplex virus. Moreover, dysregulation of TLR3 signaling has been associated with autoimmune diseases, suggesting a delicate balance in its activity. Given its significance in antiviral immunity, strategies to enhance TLR3 responses are being explored as potential antiviral therapies.

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    FAQ

    chat Skyler Brown (Verified Customer)

    How does TLR3 contribute to antiviral immune responses? Apr 13 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TLR3 plays a pivotal role in antiviral immunity, particularly through the recognition of viral RNA and activation of downstream signaling pathways, making it a potential target in viral disease treatments. Apr 13 2021

    chat Peyton Johnson (Verified Customer)

    What is the role of TLR3 in diseases like nasopharyngeal carcinoma? Apr 26 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TLR3 can be targeted by viral proteins, such as those from Epstein-Barr Virus, influencing cell proliferation and immune responses in diseases like nasopharyngeal carcinoma. Apr 26 2020

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    • mProX™ Human TLR3 Stable Cell Line (CAT#: S01YF-1023-PY209)
    • Magic™ Human TLR3 HEK293 Cell Line (CAT#: S01YF-0123-KX421)
    • Magic™ Mouse TLR3 HEK293 Cell Line with SEAP Reporter (CAT#: S01YF-0123-KX400)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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