mProX™ Human THRA Stable Cell Line

[CAT#: S01YF-1123-KX111]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Nuclear Receptor

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

THRA

Target Family

Thyroid Hormone Receptor

Target Protein Species

Human

Host Cell Type

HepG2; CHO-K1; HEK293; RL95-2; KLE

Target Classification

Nuclear Receptor

Target Research Area

Metabolic Research

Related Diseases

Hypothyroidism

Gene ID

7067

UniProt ID

P10827

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The THRA gene in humans codes for the nuclear receptor protein known as thyroid hormone receptor alpha (TR-alpha). This gene codes for a triiodothyronine nuclear hormone receptor protein. It has been demonstrated that this particular receptor, one of numerous for thyroid hormone, mediates the hormone's biological effects. Thyroid hormone actions may be mediated by distinct receptors, despite some redundancy, according to studies on knockout mice. There have been reports of alternatively spliced transcript variants encoding different isoforms. The customized THRA stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Joseph

The protocol of THRA cell line was straightforward, and the results were consistent. Dec 24 2020

chat Verified Customer

chat Michelle

The convenience of the mouse THRA KO cell line has significantly streamlined my workflow. Nov 09 2020

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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