mProX™ Human TGFBR2 Stable Cell Line

[CAT#: S01YF-1023-PY113]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1222-KX504	Magic™ Human TGFβR2 in Vitro Assay	Human		Kinase Assay

Product Information

Target Family

Kinases/Enzyme

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1;Ca Ski;SiHa

Target Classification

Kinase Cell Lines

Target Research Area

Ocular Research

Related Diseases

Loeys-Dietz Syndrome 2; Colorectal Cancer, Hereditary Nonpolyposis, Type 6

Gene ID

Human:7048

UniProt ID

Human:P37173

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The applications of TGFBR2 include its role in breast tumor growth signaling via the TGF beta-EGFR axis, its inhibition in cutaneous squamous cell carcinoma to reduce invasion and tumor growth, its involvement in the expression of carcinoma-associated genes and cell death mode in breast cancer, its potential as a key factor in the pathogenesis of visceral obesity, and its impact on cardiovascular parameters and sympathetic nerve activity in hypertensive rats. These studies highlight the diverse roles of TGFBR2 in cancer growth, gene expression, obesity, and cardiovascular function.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Casey Davis (Verified Customer)

How does TGFBR2 function in renal cell carcinoma? Jul 19 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

TGFBR2 acts as a tumor suppressor in renal cell carcinoma, with its expression being inhibited epigenetically by oncometabolites. Jul 19 2020

chat Peyton Garcia (Verified Customer)

What role does TGFBR2 play in myocardial infarction? Aug 04 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

TGFBR2 is targeted by miR-671 carried in exosomes from adipose-derived mesenchymal stem cells, alleviating myocardial infarction symptoms. Aug 04 2023

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