mProX™ Human TACR2 Stable Cell Line

[CAT#: S01YF-0923-KX51]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types
S01YF-1122-KX654	Magic™ Mouse TACR2 in Vitro Calcium Flux Assay	Mouse	CHO-K1	Calcium Flux Assay
S01YF-1122-KX655	Magic™ Rhesus monkey TACR2 in Vitro Calcium Flux Assay	Rhesus monkey	CHO-K1	Calcium Flux Assay
S01YF-1122-KX656	Magic™ Rat TACR2 in Vitro Calcium Flux Assay	Rat	CHO-K1	Calcium Flux Assay

Product Information

Target Protein

TACR2

Target Family

Tachykinin Family

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research

Related Diseases

Baritosis; Asthma

Gene ID

6865

UniProt ID

P21452

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Tachykinin neuropeptide substance K is a receptor for the protein TACR2, which can interact with G proteins to activate the phosphatidylinositol-calcium second messenger pathway. It also has something to do with GPCR signaling and peptide ligand-binding receptors. Recent research suggests that it is linked to a wide range of illnesses, including Asthma and Retinitis Pigmentosa 68. In actuality, TACR2 has a big impact on GI motility, secretion, and visceral sensitivity. Numerous other conditions, such as uterine leiomyomas, colorectal cancer, and Alzheimer's disease, have also been linked to the TACR2. In clinical therapy, TACR2 receptor antagonists have been used. The customized TACR2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

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The products definitely stand out. They are an excellent investment because of their unparalleled performance and quality. Jul 28 2023

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We are so lucky to work with creative biolabs. The quality of work, efficiency, and speed was perfect. May 27 2023

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FAQ

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