mProX™ Human SUCNR1 Stable Cell Line
[CAT#: S01YF-0923-KX49]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
SUCNR1
Target Family
Succinate Family
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cardiovascular Research; Digestive and Renal Research
Related Diseases
Renovascular Hypertension; Mooren's Ulcer
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The SUCNR1 gene, which makes up the largest group of membrane proteins in the human genome, codes for the protein succinate receptor 1 (SUCNR1). SUCNR1 promotes the growth of hematopoietic progenitor cells and may play a part in renovascular hypertension, which has been linked to renal failure, diabetes, and atherosclerosis in the past. One condition that SUCNR1 is linked to is Exudative Vitreoretinopathy 1. Peptide ligand-binding receptors and the cAMP signaling pathway are two of its associated pathways. An essential SSUCNR1 paralog is OXGR1. Furthermore, SUCNR1, like P2Y12, 13, and 14, links to Gi/o nearly exclusively, unlike P2Y1-like receptors, which preferentially stimulate Gq signaling and cause calcium release. The customized SUCNR1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Rose
The SUCNR1 cell line is suitable for our drug screening.
Jan 16 2023
Verified Customer
Leopold
Very easy to use for drug screening assay.
May 18 2023
Verified Customer
FAQ
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