mProX™ Human SLC6A3 Stable Cell Line

[CAT#: S01YF-1123-KX133]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Transporter Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

SLC6A3

Target Family

SLC Transporter

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Transporter Cell Lines

Target Research Area

CNS Research; Pain and Addiction Research

Related Diseases

Parkinsonism-Dystonia; Tobacco Addiction

Gene ID

6531

UniProt ID

Q01959

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The dopamine transporter, or DAT, is a protein that is made using instructions provided by the SLC6A3 gene. This protein carries a chemical known as dopamine into the cell by embedding itself in the membrane of specific brain nerve cells. Dopamine is released into the area between neurons in order to transfer messages, where it binds to receptors on the surface of nearby neurons. The dopamine transporter recycles dopamine in neurons from the synaptic cleft. How much and how long dopamine is present in the synaptic cleft depends on the transporter's activity. The transporter becomes a key modulator of dopamine signaling in the brain as a result of this activity. The customized SLC6A3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Donna

The SLC6A3 cell line is easy to handle and has shown consistent performance in various experimental setups. May 06 2020

chat Verified Customer

chat Nancy

I recently had the opportunity to try the human SLC6A3 cell line from Creative Biolabs. The provided instructions were clear and easy to follow. Mar 27 2022

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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