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  • mProX™ Human SLC30A3 Stable Cell Line

    [CAT#: S01YF-1123-KX131]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Transporter Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    SLC30A3
    Target Family
    SLC Transporter
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Transporter Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Hyperekplexia
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Humans have a protein called zinc transporter 3, or solute carrier family 30 member 3, which is encoded by the SLC30A3 gene. The ZnT-3 SLC30A family membrane transport protein is encoded by the SLC30A3 gene. Zinc ion accumulation inside synaptic vesicles requires ZnT-3. Certain types of memory in mice that rely on the hippocampus and amygdala require ZnT-3. Zinc transport by ZnT-3 acts via the extracellular signal-regulated kinases signaling pathway to affect memory formation. Down-regulation of ZnT-3 and ZnT-10 is necessary for the senescence of vascular smooth muscle cells brought on by angiotensin II. The customized SLC30A3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Linda

    The human SLC30A3 cell line showed good performance. It was reliable for most experiments, and the customer support team was helpful in troubleshooting. Nov 04 2022

    chat Verified Customer

    chat Karen

    The SLC30A3 cell line worked as advertised and was a cost-effective alternative in our studies. Jun 16 2023

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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