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    mProX™ Human SLC22A8 Stable Cell Line

    [CAT#: S01YF-1123-KX127]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Transporter Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-0922-KX1566 Magic™ Human SLC22A8 in Vitro Drug screening assay Human Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )

    Product Information

    Target Protein
    SLC22A8
    Target Family
    SLC Transporter
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Transporter Cell Lines
    Target Research Area
    Digestive and Renal Research; Metabolic Research
    Related Diseases
    Gout; Hyperuricemia
    Gene ID
    9376
    UniProt ID
    Q8TCC7

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The human SLC22A8 gene encodes the protein known as organic anion transporter 3 (OAT3). Organic ions, some of which are pharmaceuticals and some of which are pure toxicants, are transported and excreted via OAT3. The inward sodium gradient, which propels dicarboxylate reentry into the cytosol, indirectly supports SLC22A8 (OAT3). To drive the influx of organic anions against their concentration gradient, dicarboxylates-such as alpha-ketoglutarate-are utilized as exchange substrates within cells or recycled from the external environment. The encoded protein is an integral membrane protein that is thought to be located on the renal proximal tubule cells' basolateral membrane. The customized SLC22A8 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Matthew

    The SLC22A8 cell line is approximately lower than other brands of reagents and I got similar results. Apr 27 2023

    chat Verified Customer

    chat Kevin

    The SLC22A8 cell line was easy to use, and the customer service team was responsive and helpful. Highly recommended! Dec 17 2022

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

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    • mProX™ Human SLC22A8 Stable Cell Line (CAT#: S01YF-1123-KX127)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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