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  • mProX™ Human SLC22A6 Stable Cell Line

    [CAT#: S01YF-1123-KX126]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Transporter Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-0922-KX1565 Magic™ Human SLC22A6 in Vitro Drug screening assay Human Caco-2, MDCK, HEK293, CHO, membrane vesicles, and various transfected cells lines Activity Assay (High throughput screening assays; Large scale single dose, duplicate profiling; IC50 profiling; Ki determination assay; Substrate determination assay )

    Product Information

    Target Protein
    SLC22A6
    Target Family
    SLC Transporter
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Transporter Cell Lines
    Target Research Area
    Digestive and Renal Research; Metabolic Research
    Related Diseases
    Hyperuricemia; Fanconi-Like Syndrome
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The SLC22A6 gene in humans codes for the protein known as organic anion transporter 1 (OAT1). It belongs to the family of proteins known as organic anion transporters, or OATs. OAT1 is a transmembrane protein that is expressed in the kidneys' proximal tubular cells' basolateral membrane, the brain, the placenta, the eyes, and smooth muscles. It is essential to the movement of organic anion in the kidney. OAT1 and OAT3 work together to facilitate the uptake of a variety of comparatively tiny and hydrophilic organic anions from plasma into the kidney's proximal tubular cells' cytoplasm. It has been determined that rats, mice, rabbits, pigs, flounders, and nematodes all have OAT1 homologs. The customized SLC22A6 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Rebecca

    I have tested the mouse SLC22A6 cell line from Creative Biolabs as one of the most reliable and versatile options available. May 23 2023

    chat Verified Customer

    chat Timothy

    The SLC22A6 cell line is easy to use, and the provided protocols are clear and straightforward. Its competitive pricing compared to other similar products. Dec 20 2020

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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