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    mProX™ Human SCTR Stable Cell Line

    [CAT#: S01YF-0923-PY81]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    SCTR
    Target Family
    Glucagon Family
    Target Protein Species
    Rat
    Host Cell Type
    PC12;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Gastrinoma;Esophageal Adenosquamous Carcinoma
    Gene ID
    Rat: 81779
    UniProt ID
    Rat: P23811

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The Secretin Receptor (SCTR) has been identified as a potential diagnostic biomarker in colorectal cancer due to its hypermethylation. Additionally, SCTR has been associated with the regulation of various physiological processes. For instance, SCTR has been linked to the regulation of vasopressin expression and release in the hypothalamus, suggesting its role in osmoregulation. Furthermore, SCTR's involvement in the proliferation and migration of cancer cells has been explored, indicating its potential role in cancer progression. These findings highlight the importance of SCTR in various physiological and pathological processes, suggesting its potential as a therapeutic target.

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    FAQ

    chat Anthony (Verified Customer)

    How is SCTR hypermethylation associated with colorectal cancer? Jul 07 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Hypermethylation at CpG islands of the SCTR gene is a potential diagnostic biomarker in colorectal cancers and its precursor lesions. Jul 07 2021

    chat Christopher (Verified Customer)

    What role does the SCTR/AT1aR heteromer play in controlling Vp expression and release in the hypothalamus? Aug 07 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The SCTR-AT1aR heteromer mediates stimulatory actions of both SCT and ANGII in hypothalamic Vp expression and release as well as neuronal activities via the immediate early gene cFos. Aug 07 2022

    Related Products by Target
    • mProX™ Human SCTR Stable Cell Line (CAT#: S01YF-0923-PY81)
    • Magic™ Human SCTR CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay (CAT#: S01YF-1222-KX119)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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