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    Family stable cell lines Voltage Gated Sodium Channel Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human SCN9A Stable Cell Line

    [CAT#: S01YF-1123-KX7]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Product Information

    Target Protein
    SCN9A
    Target Family
    Voltage Gated Sodium Channel
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    Cardiovascular Research; CNS Research
    Related Diseases
    Paroxysmal Extreme Pain Disorder
    Gene ID
    6335
    UniProt ID
    Q15858

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The SCN9A gene is a member of a group of genes that give instructions on how to create sodium channels. These channels are crucial for a cell's capacity to produce and send electrical signals because they carry positively charged sodium atoms (sodium ions) into cells. One component of a sodium channel called NaV1.7, the alpha subunit, is made according to instructions from the SCN9A gene. NaV1.7 sodium channels are present in nociceptors, which are nerve cells. The peripheral nervous system, which links the brain and spinal cord to cells that sense touch, smell, and pain, includes nociceptors. The primary function of nociceptors is to transmit pain signals. The spinal cord is home to the nociceptors' cell bodies. Extending from the cell bodies are fibers known as axons that travel throughout the body to collect sensory data. The information is returned to the spinal cord by axons, which subsequently conveys it to the brain. The customized SCN9A stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human SCN9A Stable Cell Line (S01YF-1123-KX7). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Christopher (Verified Customer)

    Are there any known diseases or conditions associated with SCN9A? Jul 09 2023

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Yes, SCN9A has been implicated in conditions like hypertension and its potential role in cardiovascular diseases. Jul 09 2023

    chat Karen (Verified Customer)

    Can SCN9A be used as a therapeutic target? Mar 27 2023

    chat Sherry Smith (Creative Biolabs Scientific Support)

    While SCN9A is being studied for its potential role in various conditions, it's essential to understand its function fully before considering it as a therapeutic target. Mar 27 2023

    Related Products by Target
    • mProX™ Human SCN9A Stable Cell Line (CAT#: S01YF-1123-KX7)
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    • Magic™ Human SCN9A HEK293 Cell Line (CAT#: S01YF-0123-KX517)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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