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    mProX™ Human SCN10A Stable Cell Line

    [CAT#: S01YF-1123-KX8]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Product Information

    Target Protein
    SCN10A
    Target Family
    Voltage Gated Sodium Channel
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    Cardiovascular Research; CNS Research
    Related Diseases
    Episodic Pain Syndrome; Sodium Channelopathy-Related Small Fiber Neuropathy
    Gene ID
    6336
    UniProt ID
    Q9Y5Y9

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The SCN10A gene is a member of a group of genes that give instructions on how to create sodium channels. One component of a sodium channel called NaV1.8-the alpha subunit-is made according to instructions from the SCN10A gene. In pain-transmitting nerve cells termed nociceptors, sodium channel NaV1.8 is present. The peripheral nervous system, which links the brain and spinal cord to cells that sense touch, smell, and pain, includes nociceptors. The primary function of nociceptors is to transmit pain signals. The dorsal root ganglion, a region of the spinal cord, houses the nociceptors' cell bodies, or centers. Extending from the cell bodies are fibers known as axons that travel throughout the body to collect sensory data. Along with nociceptors, NaV1.8 sodium channels have also been discovered in heart muscle cells. By regulating the flow of sodium ions, these channels probably contribute to the maintenance of a healthy heart rhythm. The customized SCN10A stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human SCN10A Stable Cell Line (S01YF-1123-KX8). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Sandra (Verified Customer)

    What is the significance of SCN10A in episodic pain? Sep 12 2021

    chat Sherry Smith (Creative Biolabs Scientific Support)

    SCN10A have been linked to nociceptors to episodic pain. Sep 12 2021

    chat Dorothy (Verified Customer)

    Is NaV1.8 the same as SCN10A? Jan 13 2021

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Yes, the SCN10A gene encodes NaV1.8 sodium channels. Jan 13 2021

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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