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    mProX™ Human S1PR5 Stable Cell Line

    [CAT#: S01YF-0923-PY104]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX584 Magic™ Mouse S1PR5 in Vitro Calcium Flux Assay Mouse CHO-K1-Gqi5 Calcium Flux Assay

    Product Information

    Target Protein
    S1PR5
    Target Family
    Lysophospholipid Family
    Target Protein Species
    Human
    Host Cell Type
    SW480;SW620;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Immunology Research;CNS Research
    Related Diseases
    Dermatitis, Atopic, 7;Second-Degree Atrioventricular Block
    Gene ID
    Human: 53637
    UniProt ID
    Human: Q9H228

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    S1PR5, another member of the sphingosine-1-phosphate receptor family, has been recognized for its role in the nervous system. It is particularly involved in the regulation of oligodendrocyte progenitor migration, which is crucial for myelination in the central nervous system. Disruptions in S1PR5 signaling can lead to demyelinating diseases. Furthermore, S1PR5 has been linked to the modulation of natural killer cell trafficking, emphasizing its multifaceted roles in both the nervous and immune systems.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human S1PR5 Stable Cell Line (S01YF-0923-PY104). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Joseph (Verified Customer)

    What are the mechanisms of activation and drug recognition for S1PR5? Nov 17 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The structural and functional assays have demonstrated different binding modes of chemically distinct agonists of S1PRs. These studies reveal a mechanical switch that activates these receptors and provides a framework for understanding ligand selectivity and G protein coupling. Nov 17 2022

    chat Jennifer (Verified Customer)

    How does S1PR5 relate to the signaling complexes of lipid receptors? Mar 09 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    S1PR5 is one of the lipid receptors, and its signaling complexes play a crucial role in understanding ligand selectivity, G protein coupling, and receptor activation. Mar 09 2022

    Related Products by Target
    • Magic™ Human S1PR5 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay (CAT#: S01YF-1222-KX310)
    • Magic™ Human S1PR5 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay (CAT#: S01YF-1222-KX59)
    • Magic™ Human FLAG tagged S1PR5 CHO-K1 Cell Line, cAMP assay (CAT#: S01YF-1022-KX425)
    • mProX™ Human S1PR5 Stable Cell Line (CAT#: S01YF-0923-PY104)
    • Magic™ Human FLAG tagged S1PR5 CHO-K1 Gαqi5 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX426)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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