mProX™ Human RXRG Stable Cell Line

[CAT#: S01YF-1123-KX110]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Nuclear Receptor

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Lot Number

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Product Information

Target Protein

RXRG

Target Family

Retinoid X Receptor

Target Protein Species

Human

Host Cell Type

MDA-MB-231; MCF-7; CHO-K1; HEK293

Target Classification

Nuclear Receptor

Target Research Area

Cancer Research; Cardiovascular Research

Related Diseases

Hyperlipidemia; Lung Cancer

Gene ID

6258

UniProt ID

P48443

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The RXRG gene in humans codes for the nuclear receptor known as retinoid X receptor gamma, or RXR-gamma. A member of the nuclear receptor family known as retinoid X receptor (RXR) family, which is implicated in mediating the antiproliferative actions of retinoic acid (RA), is encoded by this gene. Together with the thyroid hormone, vitamin D, and retinoic acid receptors, this receptor produces heterodimers that enhance transcriptional activity on the corresponding response element as well as DNA binding. Non-small cell lung cancer cells express this gene at much lower levels. Different isoforms encoded by alternative transcriptional splice variants have been identified and described. The customized RXRG stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Dorothy

This is a very reliable RXRG overexpression cell line with high sensitivity and specificity, suitable for experiments such as flow cytometry. Aug 02 2022

chat Verified Customer

chat Michelle

The RXRG cell line has not disappointed. It consistently delivers accurate results, making my work much more impactful. Feb 02 2020

chat Verified Customer

FAQ

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