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    mProX™ Human RXFP3 Stable Cell Line

    [CAT#: S01YF-0923-KX28]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    RXFP3
    Target Family
    Relaxin Family
    Target Protein Species
    Human
    Host Cell Type
    SH-SY5Y; CHO-K1; HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Schizotypal Personality Disorder; Chromosome 5P13 Duplication Syndrome
    Gene ID
    51289
    UniProt ID
    Q9NSD7

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    RNL3/relaxin-3 has a receptor called RXFP3. The ligand's binding prevents cAMP buildup. Relaxin-3 is the primary ligand for RXFP3. According to the current research, relaxin-3 is a neurohormone that primarily regulates central nervous system function, including the regulation of reaction, upkeep of arousal, and cognitive function. Additionally, the activation of RXFP1 and RXFP3/4 by H3 relaxin results in various intracellular responses in vitro. Cell signaling processes related to the relaxin-family receptors have been studied in various cell lines transfected with the human receptors. According to reports, RXFP3 and RXFP4 couple to the inhibitory Gαi/o-protein system in CHO cells. Receptor activation causes these G proteins to be sequestered, adenylate cyclase (AC) to be inhibited, and cAMP to accumulate as a result. The customized RXFP3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human RXFP3 Stable Cell Line (S01YF-0923-KX28). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Lena (Verified Customer)

    What's the incubation time and other information of this product? Sep 15 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Rrefer to the product's datasheet found on the product's details webpage. Sep 15 2022

    chat Bob (Verified Customer)

    What's assay conditions for my cell product? Mar 09 2023

    chat Sherry Smith (Creative Biolabs Scientific Support)

    The ideal test conditions are unknown in the absence of the reference agonist. We can, however, provide a starting point to use until an agonist is found that might then be utilized to improve assay conditions. Mar 09 2023

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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