mProX™ Human RXFP2 Stable Cell Line
[CAT#: S01YF-0923-KX27]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
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InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
In terms of binding ability, RXFP2 can bind to relaxin-2, relaxin-3, and INSL-3, with INSL-3 having the highest affinity. Both the RXFP2 knockout mouse phenotype and the INSL-3 knockout mouse phenotype exhibit cryptorchidism. The gubernaculum-distributed RXFP2 that INSL-3 binds to controls the embryonic period testicle drop. In contrast, INSL-3 is insufficient to mediate healthy testicular aging. Androgen is necessary for the regulation of the suspensory ligament in testicular degeneration. The INSL-3-RXFP2 system controls not only testicular decline in male animals but also follicular atresia and corpus luteum apoptosis in female animals. Female INSL-3 mutant mice showed increased follicular atresia and early corpus luteum death. The customized RXFP2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Elizabeth
They are an excellent investment because of their unparalleled performance and quality.
Jul 21 2023
Verified Customer
David
The RXFP2 cell line showed good performance in our hands. It was reliable for most experiments, and the customer support team was helpful in troubleshooting.
May 01 2023
Verified Customer
FAQ
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