mProX™ Human PVR Stable Cell Line
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Immune Checkpoint Cell Lines
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Published Data
Fig.1 Inhibiting CD155 expression exerts a repressive effect on the growth of colon cancer cells, curtailing their proliferation significantly.
The impact of CD155 gene silencing on the proliferation of CT26 and Sw620 cell lines was investigated in this study. We conducted Western blot analysis to evaluate the effectiveness of CD155 knockdown in both CT26 and Sw620 cells. Additionally, a CCK-8 assay was carried out to assess the viability of CT26 and Sw620 cells following transfection with either scramble or siRNA CD155 (designated as 565, 566, and 567). The results presented herein are based on the average ± standard deviation obtained from three separate experiments, with statistical significance denoted as *P < 0.05 and **P < 0.01.
Ref: Zheng, Qianqian, et al. "CD 155 knockdown promotes apoptosis via AKT/Bcl-2/Bax in colon cancer cells." Journal of cellular and molecular medicine 22.1 (2018): 131-140.
Pubmed: 28816021
DOI: 10.1111/jcmm.13301
Research Highlights
Suzuki, Minako. et al. "Quantitative analysis of chest computed tomography of COVID-19 pneumonia using a software widely used in Japan." PloS one, 2023.
In this research, the focus was on identifying the most effective parameters for gauging the extent of pneumonia (pneumonia volume ratio [PVR]) and the computed tomography (CT) score attributed to COVID-19 using the Ziostation2 image analysis software (Z2; Ziosoft, Tokyo, Japan), a popular tool in Japan. A group of 53 patients (41 men and 12 women, mean age: 61.3 years) diagnosed with COVID-19 underwent chest CT scans between January 2020 and January 2021. The patients were categorized as either mild (n = 38) or severe (n = 15) based on the severity of their COVID-19 infection. The study compared PVR and CT scores obtained from Z2 under various conditions with visually assessed scores, ultimately determining the most reliable measurement condition to align with visual measurements, which was ≥-600 HU. The evaluation showed that the PVR measured by Z2 had a higher AUC compared to CT scores in assessing clinical severity, making it a valuable clinical tool for facilities utilizing Z2.
Suzuki, Minako. et al. "Quantitative analysis of chest computed tomography of COVID-19 pneumonia using a software widely used in Japan." PloS one, 2023.
Pubmed:
37871048
DOI:
10.1371/journal.pone.0287953
Deger, Mutlu. et al. "Management Patterns of Male Urethral Stricture Disease among Urologists: What Do the Guidelines Say? What Do Urologists Do?" Archivos espanoles de urologia, 2023.
This study aimed to assess and analyze the current daily clinical approach for male urethral stricture disease (MUSD) among urologists. Data were collected and analyzed through surveys and interviews with practicing urologists. The results revealed variations in techniques and success rates among urologists, highlighting the need for further standardization and improvement in the management of MUSD. The findings of this study could inform future developments in the clinical practice of MUSD.
Deger, Mutlu. et al. "Management Patterns of Male Urethral Stricture Disease among Urologists: What Do the Guidelines Say? What Do Urologists Do?" Archivos espanoles de urologia, 2023.
Pubmed:
37867333
DOI:
10.56434/j.arch.esp.urol.20237607.60
