mProX™ Human PTGIR Stable Cell Line
[CAT#: S01YF-0923-KX11]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
PTGIR
Target Family
Prostanoid Family
Target Protein Species
Human
Host Cell Type
BEAS-2B; CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cancer Research; Cardiovascular Research; Inflammation Research
Related Diseases
Erythroleukemia; Pulmonary Hypertension
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
PTGIR's cellular function is compromised by genetic flaws, which are probably rare genetic causes of FMD and SCAD. Scientists believe that 0.5% of FMD patients and 0.3% of SCAD patients, respectively, had PTGIR mutations, based on genetic screening of FMD and SCAD cohorts. These estimates need to be refined by larger research, which ought to involve more patients. This discovery and the availability of numerous medications that target this route may aid clinicians in developing customized treatment plans for FMD and SCAD patients. To completely assess the impact of this pathway on the pathophysiology of non-inflammatory stenosis and dissection found in FMD and SCAD arteries, more genetic investigations involving functionally relevant genes are needed. The customized PTGIR stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Gabriel
mProX™ Human PTGIR Stable Cell Line is perfect for my research.
Jan 21 2022
Verified Customer
Sarah
Great service.
Aug 03 2023
Verified Customer
FAQ
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