mProX™ Human PTGER3 Stable Cell Line
[CAT#: S01YF-0923-KX8]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
PTGER3
Target Family
Prostanoid Family
Target Protein Species
Human
Host Cell Type
HIO180; OVCAR-3; CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cancer Research; CNS Research; Inflammation Research; Reproductive Research
Related Diseases
Mast Cell Neoplasm; Antenatal Bartter Syndrome
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The human gene PTGER3 encodes PTGER3, a prostaglandin receptor for prostaglandin E2 (PGE2). The PTGER3 receptor performs a number of tasks. First, the capacity of aspirin and other nonsteroidal anti-inflammatory medicines to lower fever brought on by inflammation in animals and possibly humans is due to suppression of the PGE2-EP3 pathway. Then, in models of allergic conjunctivitis and contact hypersensitivity, EP3 receptor-deficient mice and/or wild type mice treated with an EP3 receptor agonist are similarly shielded from allergic reactions. Therefore, at least in mice, EP3 appears to have a significant role in lowering allergy sensitivity. Third, research on tissues from mice, guinea pigs, humans, and guinea pigs shows that PGE2 activates EP3 to cause coughing responses. The customized PTGER3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Natalie
The PTGER3 cell lines definitely stand out. They are an excellent investment because of their unparalleled performance and quality.
Dec 05 2022
Verified Customer
Andrew
We are so lucky to work with creative biolabs.
May 31 2023
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
