mProX™ Human PTGDR Stable Cell Line
[CAT#: S01YF-0923-KX5]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The PTGDR gene encodes the prostanoid D receptor (PGD2 receptor), also known as PTGDR. The PTGDR molecule has a molecular weight of 40.28 kDa and 359 amino acids. It has seven transmembrane domains, a configuration found in heterotrimeric G proteins that function as signaling receptors. Through linkage and association studies, the prostaglandin D2 receptor (PTGDR) gene has been linked to asthma and related symptoms. Functional studies using animal models and additional expression studies based on in vitro cell models also suggest a potential role for polymorphisms in the promoter region, in the differential binding of transcription factors, and consequently in PTGDR expression, which appear to be linked to the development of asthma or to susceptibility to the disease. The customized PTGDR stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
LiLi
I customized a PTGDR overexpression cell line and it was verified that the product meets my requirement.
Oct 31 2022
Verified Customer
Christopher
This cell line is very suitable for studying the PTGDR signaling pathway.
Jan 15 2023
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
