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  • mProX™ Human PRLHR Stable Cell Line

    [CAT#: S01YF-0923-KX3]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    PRLHR
    Target Family
    Prolactin-releasing Peptide Family
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research; Reproductive Research
    Related Diseases
    Body Mass Index Quantitative Trait Locus
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Because PRLHR has been identified as a prolactin-releasing peptide receptor, prolactin-releasing peptide mediates its activation. Pituitary PRLHR is highly expressed and contributes to the development of fibroids. AKT and MTOR were activated by the elevated expression of PRLHR in the patient's leiomyoma samples. When patients' leiomyoma cells are treated with PrRP-31 peptide, their PI3K/AKT/MTOR signaling and proliferation increase in comparison to healthy smooth muscle cells obtained from the myometrium. According to other findings, PRLHR and other connected factors have a significant influence in metabolic diseases. Numerous studies also point to the importance of the PrRP and PRLHR signaling pathway in the homeostatic control of eating and energy balance. The customized PRLHR stable cell line can be used in potential drug candidate screening and signaling pathway researches.

    Protocols

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    Customer Reviews

    chat Anna

    High quality and reliable PRLHR cell line. Apr 18 2023

    chat Verified Customer

    chat Mason

    We want to stick to the same system. Feb 15 2023

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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