mProX™ Human P2RY8 Stable Cell Line

[CAT#: S01YF-0923-KX25]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Lot Number

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Product Information

Target Protein

P2RY8

Target Family

P2Y Family

Target Protein Species

Human

Host Cell Type

CRLF2; Ba/F3; CHO-K1; HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Cancer Research; Cardiovascular Research

Related Diseases

B-Cell Acute Lymphoblastic Leukemia

Gene ID

286530

UniProt ID

Q86VZ1

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

P2RY8 is a transmembrane receptor that binds to and is activated most selectively by adenosine and uridine nucleotides. Adenosine and uridine nucleotides stimulate P2RY8 activity, which in turn stimulates the intracellular signaling pathway for adenylyl cyclase. P2RY8 can activate phospholipase C and the extracellular signal-regulated kinases signaling pathway after binding to nucleotides. There are also several studies that demonstrate the role of purinergic receptor signaling in a number of biological processes, including cell migration, proliferation, differentiation, and apoptosis. P2RY8 may play a role in leukemogenesis as patients with high levels of P2RY8 expression have a higher chance of developing leukemogenesis than individuals with low levels of P2RY8 expression. The customized P2RY8 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Abigail

mProX™ Human P2RY8 Stable Cell Line is very good! Jun 06 2023

chat Verified Customer

chat Matthew

The P2RY8 cell line is of superior quality, and I am confident in its reliability. Aug 20 2023

chat Verified Customer

FAQ

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