mProX™ Human P2RY11 Stable Cell Line
[CAT#: S01YF-0923-KX19]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
A member of the G-protein coupled receptors (GPCR) family, P2RY11 is a 40.3 kDa protein. The human P2RY11 is 33% identical to the human P2RY1 (its closest homolog), and it is activated by adenine but not by the uridine nucleotide, which speeds up the breakdown of phosphoinositides that are resistant to pertussis toxin as well as the production of cyclic AMP. This receptor functions as a selective purinoceptor and is connected to G protein, which promotes the phosphoinositide and adenylyl cyclase pathways. It has been discovered that naturally occurring read-through transcripts, produced by the intergenic splicing of this gene and an upstream gene called PPAN, exist. Everywhere you look, you can find the PPAN-P2RY11 read-through mRNA, which produces a fusion protein that is identical to each gene's product. Additionally, there is a connection between P2RY11 and a number of disorders, such as sleep disorder narcolepsy. The customized P2RY11 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Noah
The P2RY11 cell line is an essential tool for anyone studying drug discovery.
Jun 17 2023
Verified Customer
Sophia
The P2RY11 cell line is very good to use and is of high quality and safety.
May 27 2023
Verified Customer
FAQ
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