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    mProX™ Human P2RX1 Stable Cell Line

    [CAT#: S01YF-1023-PY252]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;Mouse bone marrow cells
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    CNS Research
    Related Diseases
    Neurogenic Bladder; Interstitial Cystitis
    Gene ID
    Human:5023
    UniProt ID
    Human:P51575

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    P2RX1 is a potential biomarker associated with immune infiltration and prognosis in lung adenocarcinoma (LUAD). It is part of an immune-related signature (CRRS) that can predict overall survival and has superior accuracy compared to clinical variables and molecular features. Low expression of P2RX1 is associated with poor overall survival and decreased immune infiltration. P2RX1 may also be a molecular marker to predict the effect of anti-thrombotic therapy in patients with acute coronary syndrome and atrial fibrillation after percutaneous coronary intervention. Additionally, P2RX1 is involved in subcutaneous adipose tissue alteration in the aging process and is regulated by thyroid hormone signaling. It is also implicated in the macrophage polarization and immune response in lung adenocarcinoma.

    Protocols

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    FAQ

    chat Cameron Brown (Verified Customer)

    How does P2RX1 contribute to inflammation in colitis? Feb 08 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    P2RX1 expression is upregulated in inflamed colon tissues, and targeting P2RX1 can improve the therapeutic efficiency of anti-TNF-α therapy in colitis models, suggesting its role in intestinal inflammation. Feb 08 2020

    chat Peyton Davis (Verified Customer)

    Can targeting P2RX1 alleviate renal ischemia/reperfusion injury? Jun 19 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Targeting P2RX1 can preserve mitochondrial dynamics and alleviate renal ischemia/reperfusion injury by influencing the formation of neutrophil extracellular traps. Jun 19 2023

    Related Products by Target
    • mProX™ Human P2RX1 Stable Cell Line (CAT#: S01YF-1023-PY252)
    • Magic™ mPro Human P2RX1 Cell Line (CAT#: S01YF-1122-KX122)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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