Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. OXER1
  3. mProX™ Human OXER1 Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP GPCR Cell Lines,Drug Discovery Tools
    Family stable cell lines Leukotriene Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human OXER1 Stable Cell Line

    [CAT#: S01YF-0923-PY96]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Protein
    OXER1
    Target Family
    Leukotriene Family
    Target Protein Species
    Human
    Host Cell Type
    MCF-7;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Nephrogenic Diabetes Insipidus
    Gene ID
    Human: 165140
    UniProt ID
    Human: Q8TDS5

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    OXER1, also known as the oxoeicosanoid receptor 1, has been implicated in various cellular processes. A study found that ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1. Additionally, nine polyphenolic molecules have been identified as putative OXER1 antagonists, suggesting their potential as anti-inflammatory and antiproliferative agents. OXER1 has also been shown to play a role in promoting cell migration in human cancer epithelial cells. Furthermore, OXER1 has been identified as a mediator of the antidepressant effects of amitriptyline, a typical tricyclic antidepressant.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human OXER1 Stable Cell Line (S01YF-0923-PY96). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Ronald (Verified Customer)

    How does OXER1 influence wound healing processes? Jan 27 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Decreasing C1P activity through inhibitors or genetic ablation of the enzyme ceramide kinase (CERK) can enhance wound healing phenotypes. This is linked to the suppression of 5-oxo-ETE biosynthesis and signaling via its receptor OXER1, suggesting a potential therapeutic approach to shift the balance from inflammation to resolution and improve wound healing rates. Jan 27 2023

    chat John (Verified Customer)

    What role does OXER1 play in cancer cell migration? May 23 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    OXER1 and its endogenous ligand play a significant role in controlling the migration of human cancer epithelial cells, such as DU-145, T47D, and Hep3B. The activation and migration phase of healing is mimicked in these cells, and the expression of OXER1 is up-regulated by its ligand 5-oxo-ETE in a time-related manner. May 23 2020

    Related Products by Target
    • mProX™ Human OXER1 Stable Cell Line (CAT#: S01YF-0923-PY96)
    • Magic™ Human FLAG tagged OXER1 HEK293T Cell Line (CAT#: S01YF-1022-KX401)
    • Magic™ Human OXER1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay (CAT#: S01YF-1222-KX151)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare