mProX™ Human NPY4R Stable Cell Line

[CAT#: S01YF-0923-PY140]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types
S01YF-1122-KX708	Magic™ Rhesus monkey NPY4R in Vitro Calcium Flux Assay	Rhesus monkey	CHO-K1	Calcium Flux Assay
S01YF-1122-KX709	Magic™ Rhesus monkey NPY4R in Vitro cAMP Assay	Rhesus monkey	CHO-K1	cAMP Assay
S01YF-1122-KX710	Magic™ Rat NPY4R in Vitro Calcium Flux Assay	Rat	CHO-K1	Calcium Flux Assay
S01YF-1122-KX711	Magic™ Rat NPY4R in Vitro cAMP Assay	Rat	CHO-K1	cAMP Assay

Product Information

Target Protein

NPY4R

Target Family

Neuropeptide Y Family

Target Protein Species

Human

Host Cell Type

A549;HT-29;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Metabolic Research

Related Diseases

Postsurgical Hypothyroidism

Gene ID

Human: 5540

UniProt ID

Human: P50391

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Neuropeptide Y receptor Y4 (NPY4R) is another member of the neuropeptide Y receptor family. Scientific studies have highlighted its role in the regulation of food intake, particularly in the inhibition of appetite. Additionally, NPY4R has been linked to the modulation of gut motility and energy homeostasis. Its expression in the gastrointestinal tract and the brain underscores its multifaceted role in both central and peripheral physiological processes.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Donna (Verified Customer)

How is NPY4R associated with obesity? Apr 28 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

Both genetic and structural variations in NPY4R might be implicated in the pathogenesis of obesity. The 10q11.22 CNV is considered the most interesting candidate gene in this region, indicating a potential role of NPY4R in obesity development. Apr 28 2022

chat Cynthia (Verified Customer)

What insights does the evolution of the neuropeptide Y receptor family provide about NPY4R? Jul 04 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

The evolution of the neuropeptide Y receptor family, including NPY4R, can be traced through gene and chromosome duplications. Understanding this evolutionary process can provide insights into the functional diversification and specialization of these receptors, including NPY4R. Jul 04 2020

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