mProX™ Human NPY2R Stable Cell Line

[CAT#: S01YF-0923-PY139]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types
S01YF-1122-KX699	Magic™ Rhesus monkey NPY2R in Vitro Calcium Flux Assay	Rhesus monkey	CHO-K1	Calcium Flux Assay
S01YF-1122-KX700	Magic™ Rhesus monkey NPY2R in Vitro cAMP Assay	Rhesus monkey	CHO-K1	cAMP Assay
S01YF-1122-KX701	Magic™ Rhesus monkey NPY2R in Vitro Radioligand Binding Assay	Rhesus monkey	CHO-K1	Radioligand Binding Assay

Product Information

Target Protein

NPY2R

Target Family

Neuropeptide Y Family

Target Protein Species

Mouse

Host Cell Type

BV-2;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research;Cardiovascular Research

Related Diseases

Temporal Lobe Epilepsy;Peripheral Artery Disease

Gene ID

Mouse: 18167

UniProt ID

Mouse: P97295

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Neuropeptide Y receptor Y2 (NPY2R) is a G-protein coupled receptor that plays a vital role in various physiological processes. In the realm of scientific research, NPY2R has been associated with the regulation of food intake, energy balance, and circadian rhythms. Furthermore, it has been implicated in the modulation of anxiety and stress responses, suggesting its potential as a therapeutic target for anxiety disorders. The receptor's involvement in the central nervous system and its interactions with other neurotransmitters make it a focal point for understanding complex neural pathways and their implications in neuropsychiatric disorders.

Protocols

Please visit our protocols page.

Customer Reviews

There are currently no Customer reviews or questions for mProX™ Human NPY2R Stable Cell Line (S01YF-0923-PY139). Click the button above to contact us or submit your feedback about this product.

FAQ

chat Matthew (Verified Customer)

How does NPY2R influence the progression of osteoarthritis? Sep 23 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

NPY2R is directly involved in cartilage homeostasis. The administration of rapamycin in vitro has been shown to counteract NPY-mediated effects, exacerbating the progression of osteoarthritis. This suggests a potential therapeutic target for managing osteoarthritis progression. Sep 23 2021

chat Michelle (Verified Customer)

Can NPY2R be associated with obesity? Aug 18 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

There is no significant association found between sequence variants in the NPY2R gene and early onset obesity. This suggests that NPY2R may not play a crucial role in the development of obesity, at least not as a sole or primary factor. Aug 18 2022

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