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    mProX™ Human NPBWR2 Stable Cell Line

    [CAT#: S01YF-0923-PY137]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    NPBWR2
    Target Family
    Neuropeptide B/W Family
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Gene ID
    Human: 2832
    UniProt ID
    Human: P48146

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Neuropeptide B/W receptor 2 (NPBWR2) has been associated with the modulation of the stress axis in chickens. Research has shown that neuropeptide W (NPW) acts as an inhibitory secretagogue for GH and prolactin via the Gi protein-coupled NPBWR2. Another study provided evidence that NPW is a potent physiological corticotropin-releasing inhibitory factor in chickens, playing a core role in suppressing the activity of the stress axis. These findings highlight the importance of NPBWR2 in the endocrine system and its potential implications in stress-related disorders.

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    FAQ

    chat Richard (Verified Customer)

    How can NPBWR2 be studied in the context of membrane protein dynamics? Jul 15 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    NPBWR2, like other membrane proteins, can be studied using time-resolved X-ray scattering in solution. This technique, combined with MD simulation, helps in tracking the dynamics of membrane proteins and identifying transient intermediate states. Jul 15 2021

    chat Helen (Verified Customer)

    What are the potential applications of NPBWR2 in drug delivery and therapeutic interventions? Mar 27 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Although specific information on NPBWR2 is limited, membrane proteins like NPBWR2 can potentially be targeted using nanodiscs. Nanodiscs are nanometer-scale vehicles used for the in vivo delivery of drugs, therapeutic lipids, and active protein complexes, providing insights into cellular signaling complexes that assemble on a membrane surface. Mar 27 2020

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    • mProX™ Human NPBWR2 Stable Cell Line (CAT#: S01YF-0923-PY137)
    • Magic™ Human FLAG tagged NPBWR2 HEK293T Gαqi5 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX477)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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