mProX™ Human NPBWR1 Stable Cell Line

[CAT#: S01YF-0923-PY136]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX671	Magic™ Mouse NPBWR1 in Vitro Calcium Flux Assay	Mouse	CHO-K1	Calcium Flux Assay

Product Information

Target Protein

NPBWR1

Target Family

Neuropeptide B/W Family

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1

Target Classification

GPCR Cell Lines

Target Research Area

Metabolic Research

Related Diseases

Lipoid Proteinosis Of Urbach And Wiethe

Gene ID

Human: 2831

UniProt ID

Human: P48145

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Neuropeptide B/W receptor 1 (NPBWR1) has been identified as a key player in various physiological processes. Research has shown that NPB/NPW, which binds to NPBWR1, has a potential role in regulating stress responses, emotion, anxiety, and fear. This receptor's involvement in energy homeostasis, pain, and emotion underscores its significance in the central nervous system. The understanding of NPBWR1's functions is crucial for potential therapeutic applications, especially in neuropsychiatric disorders.

Protocols

Please visit our protocols page.

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FAQ

chat Ashley (Verified Customer)

How does NPBWR1 influence social behavior and fear memory? Feb 12 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

NPBWR1 acts as an inhibitory regulator on a subpopulation of GABAergic neurons in the lateral division of the CeA, terminating stress responses. It plays crucial roles in regulating amygdala function during physical and social stress, impacting social behavior and fear memory. Feb 12 2023

chat Stephanie (Verified Customer)

What is the role of NPBWR1 in stress responses? Dec 12 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

NPBWR1 is involved in terminating stress responses by acting on GABAergic neurons in the lateral division of the CeA. It helps in regulating amygdala function during physical and social stress, suggesting its importance in managing stress and related behaviors. Dec 12 2021

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